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From studies deemed relevant, the experts found that titanium dioxide as a food additive is poorly absorbed by the gastrointestinal tract of mice and rats, with no adverse effects observed in short-term studies in rodents receiving titanium dioxide in their diets. No observed adverse effect levels (NOAELs) of 15,000 milligrams per kilogram of bodyweight (mg/kg BW) per day and 5,000 mg/kg BW per day—the highest doses tested—were established for mice and rats, respectively.

Anatase titanium dioxide is a popular ingredient in coatings due to its excellent UV resistance and chemical stability. Many manufacturers and businesses rely on wholesale suppliers to provide high-quality anatase titanium dioxide for their coating applications.

For that reason, the Center for Science in the Public Interest has graded titanium dioxide as a food additive that consumers should seek to “avoid.” Scientists at the nonprofit nutrition and food safety watchdog group today published a new entry for titanium dioxide in its Chemical Cuisine database of food additives.  

People eating lots of candy should be more worried about the sugar and how it can cause high blood pressure and obesity, says Westerhoff.

After oral ingestion, the absorption of titanium dioxide particles is low, however they can accumulate in the body, Maged Younes, chair of the European Food Safety Authority's expert Panel on Food Additives and Flavourings, said in a May 2021 statement.

≥ 5 % of standard sample

As the global demand for tires continues to rise, driven by increasing vehicle production and the expansion of the automotive industry, the market for titanium dioxide also experiences growth. Wholesale suppliers of TiO2 play a vital role in ensuring a stable supply chain for tire manufacturers. By sourcing high-quality titanium dioxide from reliable manufacturers, tire producers can maintain consistent product quality and performance standards.

Overall, CAS 13463-67-7 stands out as a reliable and trustworthy titanium dioxide factory that is committed to delivering top-quality products and services. With its focus on quality, sustainability, and innovation, the factory has established itself as a leader in the industry and a preferred partner for companies looking to source titanium dioxide for their dyes and pigments.

The FDA has not updated its general guidance on safety assessments since 2007. Within that time, there has been a significant increase in research on the confluence of toxicology, nanotechnology and human health. The EU updates its guidance regularly with new science available to offer proper safety assessments, with its most recent update published in 2021.

Pigment grade titanium dioxide is produced at a much larger particle size than nano grade. It is used as a colourant to whiten and brighten product formulations. Nano grade titanium dioxide is manufactured into very fine (nano) particles and is transparent and colourless. It is commonly used in sunscreens to provide effective protection from potentially harmful UV rays.

Because of their small size, nanoparticles may have unique physical and chemical properties. These properties may cause them to interact with living systems differently than larger materials with the same chemical composition (also known as bulk materials).