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  • Studies of titanium dioxide as a food additive suggest health dangers

  • Titanium dioxide (TiO2), a chemical compound with remarkable properties, is a key ingredient in numerous industrial applications, from sunscreen to paint, and from food coloring to cosmetics. The manufacturing process of this versatile substance largely revolves around specialized factories that adhere to stringent standards and innovative technologies.
  • Zinc oxide. Zinc oxide is a popular cross-linking agent for rubber and for various resins. It is essential in the formulation of solvent-borne polychloroprene adhesives. Furthermore, zinc oxide is a good UV stabilizer, has biocidal activity and has a relatively high refractive index (2.0) which makes it an efficient white pigment. Some typical properties are: density 5.6 g/cm3; particle size 0.036-3 μm; oil absorption 10–20 g/100 g; specific surface area 10–45 m2/g. Zinc oxide is produced by reaction of the metal in the vapour state with oxygen. Zinc oxide is nonporous and is quite pure. Thus, the high surface area of some grades is due to the small particle size of zinc oxide. Some grades, especially for use in the rubber industry, are surface modified by deposition of 0.2-0.4% of stearic acid, propionic acid, or light oil [47].

  • When selecting a supplier of titanium dioxide for nitrile gloves, it is crucial to consider several factors. These include
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  • In the meantime, the chemical factories of Continental Europe, principally in Germany, Austria and Belgium, had taken hold of the novelty and under the collective name of lithopone or lithophone, by numerous processes, produced various grades of the pigment, branding the respective qualities as red seal, green seal, yellow seal, blue seal, etc., or selling them under some fancy name. Of this we shall speak later on. The crusade against the use of white lead in the various countries of Continental Europe, assisted the manufacturers, to a very great extent, in marketing their products, not only to industrial concerns, as has been the case in this country, until recently, but to the general painting trade. Up to 1889 the imports into this country were comparatively small. At that time one of the largest concerns manufacturing oilcloth and linoleum in the State of New Jersey began to import and use Charlton white. Shortly after that other oilcloth manufacturers followed suit, replacing zinc white with lithopone in the making of white tablecloth, etc., and later on abandoning the use of white lead in floor cloth and linoleum. This gave an impetus to several chemical concerns, that erected plants and began to manufacture the pigment. Competition among the manufacturers and the activity of the importers induced other industries to experiment with lithopone, and the shade cloth makers, who formerly used white lead chiefly, are now among the largest consumers. Makers of India rubber goods, implement makers and paint manufacturers are also consumers of great quantities, and the demand is very much on the increase, as the nature of the pigment is becoming better understood and its defects brought under control. Large quantities find their way into floor paints, machinery paints, implement paints and enamel paints, while the flat wall paints that have of late come into such extensive use owe their existence to the use of lithopone in their makeup.

  • Wholesalers dealing in TiO2 must adhere to global safety standards, such as OSHA (Occupational Safety and Health Administration) guidelines in the United States, and the EU's REACH (Registration, Evaluation, Authorisation, and Restriction of Chemicals) regulations. These guidelines emphasize the need for proper personal protective equipment (PPE), including respirators, gloves, and goggles, during handling and transportation.
  • 2. Cosmetics With its UV-filtering properties, anatase TiO2 is a popular ingredient in sunscreens and cosmetic formulations. Its ability to scatter UV radiation effectively protects the skin from harmful sun exposure, contributing to the increasing popularity of natural and mineral makeup products.


  • As we delve into the realm of factories specializing in lithopone production, we encounter a plethora of challenges and innovations. These facilities are designed to operate efficiently, minimizing waste while maximizing output. State-of-the-art technologies facilitate precise control over the pigment's consistency and purity, attributes that are paramount in maintaining the high standards expected by consumers.
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  • Exporters of titanium dioxide coatings play a crucial role in the global distribution of this essential material. These suppliers typically specialize in the refining and processing of titanium ore into a usable form of titanium dioxide. The process involves mining the raw material, primarily ilmenite or rutile, followed by conversion into titanium dioxide through various chemical processes. The resulting product must meet stringent quality standards to ensure it performs effectively in its intended application.
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  • Duan et al. administered 125 mg/kg BW or 250 mg/kg BW of anatase TiO2 (5 nm) intragastrically to mice continuously for 30 days. The exposed mice lost body weight, whereas the relative liver, kidney, spleen and thymus weights increased. Particles seriously affected the haemostasis of the blood and the immune system. The decrease in the immune response could be the result of damage to the spleen, which is the largest immune organ in animals and plays an important role in the immune response. Powel et al. demonstrated that TiO2 NPs may trigger immune reactions of the intestine after oral intake. They showed that TiO2 NPs conjugated with bacterial lipopolysaccharide, but not TiO2 NPs or lipopolysaccharide alone, trigger the immune response in human peripheral blood mononuclear cells and in isolated intestinal tissue. This indicates that TiO2 NPs may be important mediators in overcoming normal gut-cell hyporesponsiveness to endogenous luminal molecules, which may be particularly relevant to patients with inflammatory bowel disease, which is characterized by an abnormal intestinal permeability.

  • What is titanium dioxide?

  • The commitment to excellence does not stop at production methods; it extends to the research and development of new lithopone formulationspaint lithopone factories. Pigment scientists are diligently working on enhancing the properties of lithopone to make it more durable, lighter, and adaptable to an expanding range of substrates. Their efforts promise to unlock new markets and applications for this already versatile pigment.
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  • Lithopone 30% CAS No. 1345-05-7 / Physical data

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  • 4.Used as a white pigment, the hiding power is second only to titanium dioxide, but stronger than zinc oxide. The hiding power increases as the ZnS content increases, and the light resistance also improves, but the acid resistance decreases.